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NFL Vegas Insights and Props Report Week 16

We have an interesting weekend of NFL and some great looking props to focus on. Let’s dive right in with a few Vegas Insights and as always, make sure to line shop!

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The 49ers are 5-9 against the spread (ATS) this season. Arizona opened at 2.5 point favorites and that line has since shifted to -5.5 points while the total dropped from 50.5 to 48.5 points.

With Raheem Mostert and Deebo Samuel out, the offense might have struggled a lot more had news not broken about George Kittle returning this week. If you like the 49ers to cover here, MyBookie has them at +6.5 -115. Personally, the Cardinals at -5.5 is a bit hefty, but Murray looks healthy again and the Cardinals are at home. I like Arizona to cover up to -6.5 points or I’d simply take their money line at -240 on DraftKings Sportsbook if that’s your flavor (personally, I’d rather parlay the ML).


J. Wilson o0.5 Rush TDs at +142 at DraftKings Sportsbook is a nice one in my opinion. With Mostert out, he’ll be the guy inside the 5-yard line. Wilson has shown a propensity to score when given the opportunity.

J. McKinnon at o6.5 Rec Yds -116 on FanDuel Sportsbook kind of runs hand in hand with the Cardinals covering the spread. Should the Cardinals be up more than a touchdown late in the game, McKinnon likely will be on the field instead of Wilson. A single check-down target at any time during the game cover hit over on this prop.

B. Aiyuk o5.5 Recs +110 on MyBookie seems like a steal as he’s been a target hog since Week 8. Yes, George Kittle is back. But if anything, I think that allows Aiyuk to roam free a bit more even if he is followed around by Patrick Peterson (which doesn’t seem likely on all snaps today). Similar to McKinnon, if the 49ers are throwing to come back in this one, Aiyuk should have a few more opportunities to rack up some receptions.

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